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Old March 10th, 2008 #1
Alex Linder
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Jews Are The Genetic Brothers Of Palestinians, Syrians, And Lebanese

ScienceDaily (May 9, 2000) — If a common heritage conferred peace, then perhaps the long history of conflict in the Middle East would have been resolved years ago. For, according to a new scientific study, Jews are the genetic brothers of Palestinians, Syrians and Lebanese, and they all share a common genetic lineage that stretches back thousands of years.

"Jews and Arabs are all really children of Abraham," says Harry Ostrer, M.D., Director of the Human Genetics Program at New York University School of Medicine, an author of the new study by an international team of researchers in the United States, Europe, and Israel. "And all have preserved their Middle Eastern genetic roots over 4,000 years," he says.

The researchers analyzed the Y chromosome, which is usually passed unchanged from father to son, of more than 1,000 men worldwide. Throughout human history, alterations have occurred in the sequence of chemical bases that make up the DNA in this so-called male chromosome, leaving variations that can be pinpointed with modern genetic techniques. Related populations carry the same specific variations. In this way, scientists can track descendants of large populations and determine their common ancestors.

Specific regions of the Y chromosome were analyzed in 1,371 men from 29 worldwide populations, including Jews and non-Jews from the Middle East, North Africa, sub-Saharan Africa, and Europe.

The study, published in the May 9 issue of the Proceedings of the National Academy of Sciences, found that Jewish men shared a common set of genetic signatures with non-Jews from the Middle East, including Palestinians, Syrians, and Lebanese, and these signatures diverged significantly from non-Jewish men outside of this region. Consequently, Jews and Arabs share a common ancestor and are more closely related to one another than to non-Jews from other areas of the world.

The study also revealed that despite the complex history of Jewish migration in the Diaspora (the time since 556 B.C. when Jews migrated out of Palestine), Jewish communities have generally not intermixed with non-Jewish populations. If they had, then Jewish men from different regions of the world would not share the same genetic signatures in their Y chromosome.

"Because ancient Jewish law states that Jewish religious affiliation is assigned maternally, our study afforded the opportunity to assess the contribution of non-Jewish men to present-day Jewish genetic diversity," says Michael Hammer, Ph.D., from the University of Arizona, Tucson, who is the lead author of the new study. "It was surprising to see how significant the Middle Eastern genetic signal was in Jewish men from different communities in the Diaspora," he says.

The authors of this study are: Dr. Ostrer from NYU School of Medicine; Michael F. Hammer, Alan J. Redd, Elizabeth T. Wood, M. Roxane Bonner, Hamdi Jarjanazil, and Tanya Karafet from the University of Arizona, Tucson; Silvana Santachlara-Benerecetti, University of Pavia, Italy; Ariella Oppenheim, Hebrew University of Jerusalem, Israel; Mark A. Jobling, University of Leicester, England; Trefor Jenkins, University of Witwatersrand, Johannesburg, South Africa; and Batsheva Bonne-Tamar, Tel Aviv University, Israel.

Adapted from materials provided by New York University Medical Center And School Of Medicine.

http://www.sciencedaily.com/releases...0509003653.htm
 
Old October 30th, 2008 #2
Anne
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Do Jews belong to one particular Y Haplogroup? R1b is associated with Western Europeans, but I think the Jews have hijacked it to some degree. I read the National Geographic book "Deep Ancestry: Inside the Genographic Project", but I'm suspicious since they like to give the impression that our ancestors have been mingling for eons.
 
Old December 3rd, 2014 #3
Theodore
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Quote:
Originally Posted by Anne View Post
Do Jews belong to one particular Y Haplogroup? R1b is associated with Western Europeans, but I think the Jews have hijacked it to some degree. I read the National Geographic book "Deep Ancestry: Inside the Genographic Project", but I'm suspicious since they like to give the impression that our ancestors have been mingling for eons.
Good Question. Ashkenaz have roughly 30-50% R1b. A lot of it can also be attributed to Armenians who also have a high degree of R1b.. But of a particular type, like you mentioned, that is 1500 years older than Western European R1b.
 
Old October 30th, 2008 #4
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Most Jews aren't actually semites but the descendants of Turkic Khazars.
 
Old October 31st, 2008 #5
tuisto
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Origin of the Hebrews

Earliest history:

The Hebrews' land of origin is not, as is widely believed, Chaldea.
They migrated to the contrary as strangers to Chaldea and were
treated as such and chased away from their land.
(Moses 11/27-32)
There is a description of how Chara, youngest son of Tharah, was killed by the Chaldeans.
In another reference (2 Ezra 9/7) it says: "Since the days of our fathers
have we been in a great trespass unto this day; and for our iniquities have we, our kings and our priests, been delivered into the hands of the kings of the lands, to the sword, and to a spoil, and to confusion of face, as it is this day."

Today's s know very well about these things and how Chaldeans despised them.

In 1 Moses 10/21 we are told about Shem and in 11/27 about Abraham.

In 1 Moses 10/30 it says: "And their dwelling was from Me-sha, as thou goest unto Se-phar a mount of the east."

...which is the area of Saba located in the utmost south of Arabia.

Shem is called a son of Noah, which is a -lie.

Nehemia as well as Ezra are - like "Einsteins famous energy-formula - not
originally jewish but copied and perverted stories taken from Babilus.

The story of Moses is stolen from the great king Sargon I., who lived
2300 years before Moses.

The -scribes have done nothing but stolen different stories from all over
and declared it as their own. Only within their inner circles they know about it and are amused about the gullibility of the goyim world-wide.

At the time of Celsius these things were still well known.
The place described in 1 Moses 10/30 is located where the Red Sea is narrowest, at the foot of the Ebal mountains.
The chief-tain of the abominable tribe, who lived there was cast-off from
the Shabeer tribe and went by the name of Ail Habr. The originally called Habrits later became "Hebrews".
Cast-offs from other tribes as well as slaves joint Abil Habr and are the
fore-fathers of the contemporary Spielberg and Co.

Abil Habr later conquered the island Bara (Perim) on the other side, which belonged to the Reich of Egypt and made the Ethiopean Amchar and Chabbilla tribes to their allies.

Together they went until the land of the pitch-black niggers Ugan (Uganda)
and conquered it completely.
The middle of this land is since called "Habr" until this very day.

This land practiced polygamy as based on their laws.
When a terrible venereal disease plaged him, Abil Habr asked a well known sorcerer from the tribe of the Geniter from Sin-ai ("Sin-land") for help.
He was known to practice blood sacrifice in order to get the favor of his god.

This sorcerer introduced the tribe to the circumscision.
Abraham, of the same bloodline as Abil Habr, was later visited by the evil spirit "Ani ha El Shaddai" demanding a variety of blood sacrifices and established a covenant with those who are known to be jews.

When Abil Habr tried to attack the land of Habash. The king of Habash asked Pharao Sesostris I., a relative by blood, for help. He provided a fleet.
At Har the Egyptian navy defeated Abil Habr completely, but not all got killed.
They dispersed.

In 1 Moses (Genesis)17/1 it says in the original: Ani ha El Shaddai" which means translated: "I am God the Devil".
Where-ever the Habrites, a tribe of wildly mixed people settled down misery followed.

The lineage of Shem, the "Semites", had nothing in common with
the Habrits/Hebrews but the lying jew over the centuries pretended to be
Semites, which is absurd.

Hebrews are a mixture of so called "Aryan" (highest percentage!), Asians, Negroids and to a certain extent also Semites.
Habr was a Malaien sea-pirate, whose closest allies were nothing but scum.
These wildly mixed people were never able to form a decent folk.

Never should they be called "Semites".

When the Khazars, an "Aryan" tribe, started to mix with those abominable Hebrews, the "Semitic" traces in jews became less than 10%.
Jews are therefore to be considered as a foremost "ARYAN" mixture.

Linders references to dubious studies coming from jew-ni-versities caused two reactions in me:
1. wanted to cry...
2. wanted to laugh...

I suppressed both and went to work instead.

Hope a few VNN-readers will appreciate it.
 
Old May 21st, 2009 #6
Mark Faust
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Default Blooms disease, or is it just being a jew?

http://www.mazornet.com/mazornet/gen...m_syndrome.htm

1 in 110 Jews? More like 1 in 2


Symptoms
Affected Individuals, who have Bloom's Syndrome, typically have the following physical characteristics:
· Short stature
· A narrow face with prominent nose
· Skin color changes in the face. Change more noticeable after sunlight exposure
· Butterfly-shaped facial rash, similar to rash caused by Lupus Erythematosis
· A high pitched voice
· An increased susceptibility to infections and respiratory illness
· An increased susceptibility to cancer and leukemia
· Some may also have mental retardation
 
Old June 5th, 2010 #7
Alex Linder
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Genes set Jews apart, study finds

Those of European descent are more closely related with one another than with their fellow countrymen, say researchers who were primarily studying genetic diseases.

By Thomas H. Maugh II, Los Angeles Times

June 3, 2010

Jews of European descent living on opposite sides of the globe are more closely related to one another than they are to their fellow countrymen, according to the largest study ever conducted of what it means genetically to be Jewish. Ashkenazis, the primary group descended from European Jews, are all as closely related as fourth or fifth cousins would be, the study found.

"Jews really are different from their non-Jewish neighbors," said Dr. Harry Ostrer, a geneticist at the New York University Langone Medical Center, coauthor of the study appearing Thursday in the American Journal of Human Genetics.

They are not different enough to be considered a separate race, as some experts have argued, he added, but definitely are a "distinct population" — the result, presumably, of cultural separation down through thousands of years.

The study, which was conducted primarily to further medical knowledge of genetic diseases, rejected a highly controversial idea that Ashkenazi Jews are descended from Khazars in Eastern Europe who converted to Judaism — an idea that has recently been used in an attempt to discredit the idea that Jews belong in Israel because it is their historic homeland.

The study shows that there is "clearly a shared genetic common ancestry among geographically diverse populations consistent with oral tradition and culture …and that traces back to the Middle East," said geneticist Sarah A. Tishkoff of the University of Pennsylvania, who was not involved in the study. "Jews have assimilated to some extent, but they clearly retain their common ancestry."

Said Joe Berkofsky, a spokesman for the Jewish Federations of North America: "This finding in a way underscores what Jewish Federations believe and act upon through our central mission, which is to care for and protect Jews around the world, no matter where they are."

Although the study sheds light on Jewish history — providing new information about the separation between North African and European Jews 2,500 years ago and the near extinction of European Jews in the Middle Ages — its major goal is to identify genes for many diseases that are more common in Jewish groups, such as breast cancer, Gaucher's disease and Tay-Sachs.

The higher incidence of those diseases among "Abraham's children" will allow scientists to more readily find genes that causes the illnesses and then extend that knowledge to the general population, said geneticist Gil Atzmon of Yeshiva University's Albert Einstein College of Medicine in New York, coauthor of the paper.

The study examined 237 Jewish individuals from seven regions of the world, comparing them with 418 non-Jewish people from the same regions. Each of the Jewish subjects had all four grandparents from the same population.

The researchers studied about 160,000 sites across the entire genome, providing a great deal more information about the population than has ever been available.

Previous studies had found similar results by looking at smaller populations and considering only blood groups, mitochondrial DNA (a type of DNA passed down by mothers) or Y chromosomes (passed down by fathers).

The Jewish people, according to archaeologists, originated in Babylon and Persia between the 4th and 6th centuries BC. The modern-day Jews most closely related to that original population are those in Iran, Iraq and Syria, whose closest non-Jewish relatives are the Druze, Bedouins and Palestinians, the study found.

Sometime in that period, the Middle Eastern and European Jews diverged and the European branch began actively proselytizing for converts.

At the height of the Roman Empire, about 10% of the empire's population was Jewish, although the bulk of them were converts. Some Khazars were also incorporated during this period.

"That explains why so many European and Syrian Jews have blue eyes and blond hair," Ostrer says. It also explains another of the team's findings — that the population most closely related genetically to European Jews are Italians.

The data also show what the researchers call a "bottleneck" in the Jewish population during the Middle Ages. The population of European Jews shrunk below 50,000 during that period because of disease, prejudice, anti-Semitic edicts and the Crusades, Atzmon said.

Afterward, however, an easing of restrictions led to what is known as the "demographic miracle," in which the Jewish population rose twice as fast as that of other Europeans, reaching more than 5 million by the 19th century.

[email protected]

http://www.latimes.com/news/science/...,7364243.story
 
Old July 13th, 2012 #8
Rick Ronsavelle
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Default jews are 3-5 percent nigger

In the Book of Kings, Solomon is depicted as an international businessman of sorts who sent ships from the port of Etzion-Geber, near modern day Eilat, to trade precious metals and other goods with various parts of the world, including Africa. Solomon also famously received a visit from the Queen of Sheba, who is thought to be from what is presently Ethiopia.

Now, a new scientific paper offers a genetic timeline that could support these biblical tales. The paper builds on two studies published last summer that were the first to use genome-wide analyses to trace the history of the Jewish people through DNA.

“It demonstrated that there was a biological basis for Jewishness,” said Dr. Harry Ostrer, director of the human genetics program at the New York University School of Medicine, who led one of the studies.
Related

Among its many findings, Ostrer’s paper indicated that Jews have African ancestry — an observation that David Reich, associate professor of genetics at Harvard Medical School, and his colleagues decided to explore further.

Reich’s team analyzed more than half a million DNA markers across the entire genomes of people from seven diverse Jewish populations — including Ashkenazim from northern Europe; Sephardim from Italy, Turkey and Greece, and Mizrahim from Syria, Iraq and Iran. They then compared the genetic data with DNA from 15 sub-Saharan African populations.

Reporting in the April issue of PLoS Genetics, the researchers found that modern day Jews can attribute about 3% to 5% of their ancestry to sub-Saharan Africans, and that the exchange of genes between Jews and sub-Saharan Africans occurred approximately 72 generations, or about 2,000 years, ago.

Priya Moorjani, a doctoral student in Reich’s lab who led the research, was surprised that the degree of African DNA was so consistent across the various Jewish populations. She had expected, for example, that North African and Middle Eastern Jews would have a greater degree of genetic mingling than Europeans, based on their geographic proximities.

So the findings, Moorjani said, may point to a shared ancestry among the various Jewish groups. “It’s definitely suggestive that most Jewish populations have a common ancestral population,” she said.

Although the Harvard team couldn’t determine where exactly the exchange of genes took place, the results complement historians’ understanding of the Jewish narrative.

“This is interesting, and it gives me food for thought,” said Norman Stillman, a professor of Judaic history at the University of Oklahoma. “Does it prove something historically specific beyond the fact that we know the Jewish bloodline was open to some extent throughout history? No. But it fits in with the rest.”

Lawrence Schiffman, a professor of Hebrew and Judaic studies at Yeshiva University, said two time periods came to mind that could support the geneticists’ findings. The first is during the First Temple Period, between about 950 B.C.E. and 600 B.C.E., when Solomon’s kingdom would have had contact with Africans.

Or, Schiffman said, the mixing of populations could have taken place a bit later, during the Hellenistic period, from about 320 B.C.E. to 30 B.C.E., when Jews were living all over the southern shore of the Mediterranean Sea and could have come into contact with Africans to the south of them.

Yet even though the biblical accounts offer possible explanations for the Reich lab’s findings, Schiffman stresses that he and other social scientists can only offer historical interpretations of the genetic data. “The facts are the ones that scientists are developing; the theories are what [historians] have,” he said. “We now have to take what they are giving us, and we have to add it to our picture of history.”

Stillman pointed out that Jews are often thought of as an insular group, because they tended to marry within their community. “But,” he said, “that doesn’t mean there wasn’t, all throughout history, an inflow of others into the group.”

As Reich sees it, genetics and history are not actually so disparate. His work, he said, is “a kind of complementary way of studying history.”

Contact Gianna Palmer at [email protected]

http://forward.com/articles/140721/g...ies-to-africa/
 
Old August 29th, 2012 #9
Alex Linder
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DNA links prove Jews are a ‘race,' says genetics expert

Conjuring fear of Nazism and anti-Semitism, Jews recoil from the thought that Judaism might be a race, but medical geneticist Harry Ostrer insists the 'biological basis of Jewishness' cannot be ignored.

By Jon Entine May.07, 2012 | 10:51 AM | 116

In his new book, “Legacy: A Genetic History of the Jewish People,” Harry Ostrer, a medical geneticist and professor at Albert Einstein College of Medicine in New York, claims that Jews are different, and the differences are not just skin deep. Jews exhibit, he writes, a distinctive genetic signature. Considering that the Nazis tried to exterminate Jews based on their supposed racial distinctiveness, such a conclusion might be a cause for concern. But Ostrer sees it as central to Jewish identity.

“Who is a Jew?” has been a poignant question for Jews throughout our history. It evokes a complex tapestry of Jewish identity made up of different strains of religious beliefs, cultural practices and blood ties to ancient Palestine and modern Israel. But the question, with its echoes of genetic determinism, also has a dark side.

Geneticists have long been aware that certain diseases, from breast cancer to Tay-Sachs, disproportionately affect Jews. Ostrer, who is also director of genetic and genomic testing at Montefiore Medical Center, goes further, maintaining that Jews are a homogeneous group with all the scientific trappings of what we used to call a “race.”

Related articles at the Forward
• Genes tell tale of Jewish ties to Africa
• The ties that bind
• The other Jewish genetic diseases

For most of the 3,000-year history of the Jewish people, the notion of what came to be known as “Jewish exceptionalism” was hardly controversial. Because of our history of inmarriage and cultural isolation, imposed or self-selected, Jews were considered by gentiles (and usually referred to themselves) as a “race.” Scholars from Josephus to Disraeli proudly proclaimed their membership in “the tribe.”

Ostrer explains how this concept took on special meaning in the 20th century, as genetics emerged as a viable scientific enterprise. Jewish distinctiveness might actually be measurable empirically. In “Legacy,” he first introduces us to Maurice Fishberg, an upwardly mobile Russian-Jewish immigrant to New York at the fin de siècle. Fishberg fervently embraced the anthropological fashion of the era, measuring skull sizes to explain why Jews seemed to be afflicted with more diseases than other groups — what he called the “peculiarities of the comparative pathology of the Jews.” It turns out that Fishberg and his contemporary phrenologists were wrong: Skull shape provides limited information about human differences. But his studies ushered in a century of research linking Jews to genetics.

Ostrer divides his book into six chapters representing the various aspects of Jewishness: Looking Jewish, Founders, Genealogies, Tribes, Traits and Identity. Each chapter features a prominent scientist or historical figure that dramatically advanced our understanding of Jewishness. The snippets of biography lighten a dense forest of sometimes-obscure science. The narrative, which consists of a lot of potboiler history, is a slog at times. But for the specialist and anyone touched by the enduring debate over Jewish identity, this book is indispensable.

“Legacy” may cause its readers discomfort. To some Jews, the notion of a genetically related people is an embarrassing remnant of early Zionism that came into vogue at the height of the Western obsession with race, in the late 19th century. Celebrating blood ancestry is divisive, they claim: The authors of “The Bell Curve” were vilified 15 years ago for suggesting that genes play a major role in IQ differences among racial groups.

Furthermore, sociologists and cultural anthropologists, a disproportionate number of whom are Jewish, ridicule the term “race,” claiming there are no meaningful differences between ethnic groups. For Jews, the word still carries the especially odious historical association with Nazism and the Nuremberg Laws. They argue that Judaism has morphed from a tribal cult into a worldwide religion enhanced by thousands of years of cultural traditions.

A people, a religion or both?

Is Judaism a people or a religion? Or both? The belief that Jews may be psychologically or physically distinct remains a controversial fixture in the gentile and Jewish consciousness, and Ostrer places himself directly in the line of fire. Yes, he writes, the term “race” carries nefarious associations of inferiority and ranking of people. Anything that marks Jews as essentially different runs the risk of stirring either anti- or philo-Semitism. But that doesn’t mean we can ignore the factual reality of what he calls the “biological basis of Jewishness” and “Jewish genetics.” Acknowledging the distinctiveness of Jews is “fraught with peril,” but we must grapple with the hard evidence of “human differences” if we seek to understand the new age of genetics.

Although he readily acknowledges the formative role of culture and environment, Ostrer believes that Jewish identity has multiple threads, including DNA. He offers a cogent, scientifically based review of the evidence, which serves as a model of scientific restraint.

“On the one hand, the study of Jewish genetics might be viewed as an elitist effort, promoting a certain genetic view of Jewish superiority,” he writes. “On the other, it might provide fodder for anti-Semitism by providing evidence of a genetic basis for undesirable traits that are present among some Jews. These issues will newly challenge the liberal view that humans are created equal but with genetic liabilities.”

Jews, he notes, are one of the most distinctive population groups in the world because of our history of endogamy. Jews — Ashkenazim in particular — are relatively homogeneous despite the fact that they are spread throughout Europe and have since immigrated to the Americas and back to Israel. The Inquisition shattered Sephardi Jewry, leading to far more incidences of intermarriage and to a less distinctive DNA.

In traversing this minefield of the genetics of human differences, Ostrer bolsters his analysis with volumes of genetic data, which are both the book’s greatest strength and its weakness. Two complementary books on this subject — my own “Abraham’s Children: Race, Identity, and the DNA of the Chosen People” and “Jacob’s Legacy: A Genetic View of Jewish History” by Duke University geneticist David Goldstein, who is well quoted in both “Abraham’s Children” and “Legacy” — are more narrative driven, weaving history and genetics, and are consequently much more congenial reads.

A ‘people’

The concept of the “Jewish people” remains controversial. The Law of Return, which establishes the right of Jews to come to Israel, is a central tenet of Zionism and a founding legal principle of the State of Israel. The DNA that tightly links Ashkenazi, Sephardi and Mizrahi, three prominent culturally and geographically distinct Jewish groups, could be used to support Zionist territorial claims — except, as Ostrer points out, some of the same markers can be found in Palestinians, our distant genetic cousins, as well. Palestinians, understandably, want their own right of return.

That disagreement over the meaning of DNA also pits Jewish traditionalists against a particular strain of secular Jewish liberals that has joined with Arabs and many non-Jews to argue for an end to Israel as a Jewish nation. Their hero is Shlomo Sand, an Austrian-born Israeli historian who reignited this complex controversy with the 2008 publication of “The Invention of the Jewish People.”

Sand contends that Zionists who claim an ancestral link to ancient Palestine are manipulating history. But he has taken his thesis from novelist Arthur Koestler’s 1976 book, “The Thirteenth Tribe,” which was part of an attempt by post-World War II Jewish liberals to reconfigure Jews not as a biological group, but as a religious ideology and ethnic identity.

The majority of the Ashkenazi Jewish population, as Koestler, and now Sand, writes, are not the children of Abraham but descendants of pagan Eastern Europeans and Eurasians, concentrated mostly in the ancient Kingdom of Khazaria in what is now Ukraine and Western Russia. The Khazarian nobility converted during the early Middle Ages, when European Jewry was forming.

Although scholars challenged Koestler’s and now Sand’s selective manipulation of the facts — the conversion was almost certainly limited to the tiny ruling class and not to the vast pagan population — the historical record has been just fragmentary enough to titillate determined critics of Israel, who turned both Koestler’s and Sand’s books into roaring best-sellers.

Fortunately, re-creating history now depends not only on pottery shards, flaking manuscripts and faded coins, but on something far less ambiguous: DNA. Ostrer’s book is an impressive counterpoint to the dubious historical methodology of Sand and his admirers. And, as a co-founder of the Jewish HapMap — the study of haplotypes, or blocks of genetic markers, that are common to Jews around the world — he is well positioned to write the definitive response.

In accord with most geneticists, Ostrer firmly rejects the fashionable postmodernist dismissal of the concept of race as genetically naive, opting for a more nuanced perspective.

Mapping the human gene

When the human genome was first mapped a decade ago, Francis Collins, then head of the National Genome Human Research Institute, said: “Americans, regardless of ethnic group, are 99.9% genetically identical.” Added J. Craig Venter, who at the time was chief scientist at the private firm that helped sequenced the genome, Celera Genomics, “Race has no genetic or scientific basis.” Those declarations appeared to suggest that “race,” or the notion of distinct but overlapping genetic groups, is “meaningless.”

But Collins and Venter have issued clarifications of their much-misrepresented comments. Almost every minority group has faced, at one time or another, being branded as racially inferior based on a superficial understanding of how genes peculiar to its population work. The inclination by politicians, educators and even some scientists to underplay our separateness is certainly understandable. But it’s also misleading. DNA ensures that we differ not only as individuals, but also as groups.

However slight the differences (and geneticists now believe that they are significantly greater than 0.1%), they are defining. That 0.1% contains some 3 million nucleotide pairs in the human genome, and these determine such things as skin or hair color and susceptibility to certain diseases. They contain the map of our family trees back to the first modern humans.

Both the human genome project and disease research rest on the premise of finding distinguishable differences between individuals and often among populations. Scientists have ditched the term “race,” with all its normative baggage, and adopted more neutral terms, such as “population” and “clime,” which have much of the same meaning. Boiled down to its essence, race equates to “region of ancestral origin.”

‘Jewish diseases’

Ostrer has devoted his career to investigating these extended family trees, which help explain the genetic basis of common and rare disorders. Today, Jews remain identifiable in large measure by the 40 or so diseases we disproportionately carry, the inescapable consequence of inbreeding. He traces the fascinating history of numerous “Jewish diseases,” such as Tay-Sachs, Gaucher, Niemann-Pick, Mucolipidosis IV, as well as breast and ovarian cancer. Indeed, 10 years ago I was diagnosed as carrying one of the three genetic mutations for breast and ovarian cancer that mark my family and me as indelibly Jewish, prompting me to write “Abraham’s Children.”

Like East Asians, the Amish, Icelanders, Aboriginals, the Basque people, African tribes and other groups, Jews have remained isolated for centuries because of geography, religion or cultural practices. It’s stamped on our DNA. As Ostrer explains in fascinating detail, threads of Jewish ancestry link the sizable Jewish communities of North America and Europe to Yemenite and other Middle Eastern Jews who have relocated to Israel, as well as to the black Lemba of southern Africa and to India’s Cochin Jews. But, in a twist, the links include neither the Bene Israel of India nor Ethiopian Jews. Genetic tests show that both groups are converts, contradicting their founding myths.

Why, then, are Jews so different looking, usually sharing the characteristics of the surrounding populations? Think of red-haired Jews, Jews with blue eyes or the black Jews of Africa. Like any cluster — a genetic term Ostrer uses in place of the more inflammatory “race” — Jews throughout history moved around and fooled around, although mixing occurred comparatively infrequently until recent decades. Although there are identifiable gene variations that are common among Jews, we are not a “pure” race. The time machine of our genes may show that most Jews have a shared ancestry that traces back to ancient Palestine but, like all of humanity, Jews are mutts.

About 80% of Jewish males and 50% of Jewish females trace their ancestry back to the Middle East. The rest entered the “Jewish gene pool” through conversion or intermarriage. Those who did intermarry often left the faith in a generation or two, in effect pruning the Jewish genetic tree. But many converts became interwoven into the Jewish genealogical line. Reflect on the iconic convert, the biblical Ruth, who married Boaz and became the great-grandmother of King David. She began as an outsider, but you don’t get much more Jewish than the bloodline of King David!

Jewish intelligence

To his credit, Ostrer also addresses the third rail of discussions about Jewishness and race: the issue of intelligence. Jews were latecomers to the age of freethinking. While the Enlightenment swept through Christian Europe in the 17th century, the Haskalah did not gather strength until the early 19th century. By the beginning of the new millennium, however, Jews were thought of as among the smartest people on earth. The trend is most prominent in America, which has the largest concentration of Jews outside Israel and a history of tolerance.

Although Jews make up less than 3% of the population, they have won more than 25% of the Nobel Prizes awarded to American scientists since 1950. Jews also account for 20% of this country’s chief executives and make up 22% of Ivy League students. Psychologists and educational researchers have pegged their average IQ at 107.5 to 115, with their verbal IQ at more than 120, a stunning standard deviation above the average of 100 found in those of European ancestry. Like it or not, the IQ debate will become an increasingly important issue going forward, as medical geneticists focus on unlocking the mysteries of the brain.

Many liberal Jews maintain, at least in public, that the plethora of Jewish lawyers, doctors and comedians is the product of our cultural heritage, but the science tells a more complex story. Jewish success is a product of Jewish genes as much as of Jewish moms.

Is it “good for the Jews” to be exploring such controversial subjects? We can’t avoid engaging the most challenging questions in the age of genetics. Because of our history of endogamy, Jews are a goldmine for geneticists studying human differences in the quest to cure disease. Because of our cultural commitment to education, Jews are among the top genetic researchers in the world.

As humankind becomes more genetically sophisticated, identity becomes both more fluid and more fixed. Jews in particular can find threads of our ancestry literally anywhere, muddying traditional categories of nationhood, ethnicity, religious belief and “race.” But such discussions, ultimately, are subsumed by the reality of the common shared ancestry of humankind. Ostrer’s “Legacy” points out that — regardless of the pros and cons of being Jewish — we are all, genetically, in it together. And, in doing so, he gets it just right.

Jon Entine is the founder and director of the Genetic Literacy Project at George Mason University, where he is senior research fellow at the Center for Health and Risk Communication.

http://www.haaretz.com/jewish-world/...xpert-1.428664
 
Old October 15th, 2014 #10
Alex Linder
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“the central and eastern European Jewish population, known as Ashkenazi Jews, from whom most American Jews are descended, started from a founding population of about 350 people between 600 and 800 years ago.”

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Old August 29th, 2012 #11
Alex Linder
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DNA links prove Jews are a ‘race,' says genetics expert

Conjuring fear of Nazism and anti-Semitism, Jews recoil from the thought that Judaism might be a race, but medical geneticist Harry Ostrer insists the 'biological basis of Jewishness' cannot be ignored.

By Jon Entine May.07, 2012 | 10:51 AM | 116

In his new book, “Legacy: A Genetic History of the Jewish People,” Harry Ostrer, a medical geneticist and professor at Albert Einstein College of Medicine in New York, claims that Jews are different, and the differences are not just skin deep. Jews exhibit, he writes, a distinctive genetic signature. Considering that the Nazis tried to exterminate Jews based on their supposed racial distinctiveness, such a conclusion might be a cause for concern. But Ostrer sees it as central to Jewish identity.

“Who is a Jew?” has been a poignant question for Jews throughout our history. It evokes a complex tapestry of Jewish identity made up of different strains of religious beliefs, cultural practices and blood ties to ancient Palestine and modern Israel. But the question, with its echoes of genetic determinism, also has a dark side.

Geneticists have long been aware that certain diseases, from breast cancer to Tay-Sachs, disproportionately affect Jews. Ostrer, who is also director of genetic and genomic testing at Montefiore Medical Center, goes further, maintaining that Jews are a homogeneous group with all the scientific trappings of what we used to call a “race.”

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For most of the 3,000-year history of the Jewish people, the notion of what came to be known as “Jewish exceptionalism” was hardly controversial. Because of our history of inmarriage and cultural isolation, imposed or self-selected, Jews were considered by gentiles (and usually referred to themselves) as a “race.” Scholars from Josephus to Disraeli proudly proclaimed their membership in “the tribe.”

Ostrer explains how this concept took on special meaning in the 20th century, as genetics emerged as a viable scientific enterprise. Jewish distinctiveness might actually be measurable empirically. In “Legacy,” he first introduces us to Maurice Fishberg, an upwardly mobile Russian-Jewish immigrant to New York at the fin de siècle. Fishberg fervently embraced the anthropological fashion of the era, measuring skull sizes to explain why Jews seemed to be afflicted with more diseases than other groups — what he called the “peculiarities of the comparative pathology of the Jews.” It turns out that Fishberg and his contemporary phrenologists were wrong: Skull shape provides limited information about human differences. But his studies ushered in a century of research linking Jews to genetics.

Ostrer divides his book into six chapters representing the various aspects of Jewishness: Looking Jewish, Founders, Genealogies, Tribes, Traits and Identity. Each chapter features a prominent scientist or historical figure that dramatically advanced our understanding of Jewishness. The snippets of biography lighten a dense forest of sometimes-obscure science. The narrative, which consists of a lot of potboiler history, is a slog at times. But for the specialist and anyone touched by the enduring debate over Jewish identity, this book is indispensable.

“Legacy” may cause its readers discomfort. To some Jews, the notion of a genetically related people is an embarrassing remnant of early Zionism that came into vogue at the height of the Western obsession with race, in the late 19th century. Celebrating blood ancestry is divisive, they claim: The authors of “The Bell Curve” were vilified 15 years ago for suggesting that genes play a major role in IQ differences among racial groups.

Furthermore, sociologists and cultural anthropologists, a disproportionate number of whom are Jewish, ridicule the term “race,” claiming there are no meaningful differences between ethnic groups. For Jews, the word still carries the especially odious historical association with Nazism and the Nuremberg Laws. They argue that Judaism has morphed from a tribal cult into a worldwide religion enhanced by thousands of years of cultural traditions.

A people, a religion or both?

Is Judaism a people or a religion? Or both? The belief that Jews may be psychologically or physically distinct remains a controversial fixture in the gentile and Jewish consciousness, and Ostrer places himself directly in the line of fire. Yes, he writes, the term “race” carries nefarious associations of inferiority and ranking of people. Anything that marks Jews as essentially different runs the risk of stirring either anti- or philo-Semitism. But that doesn’t mean we can ignore the factual reality of what he calls the “biological basis of Jewishness” and “Jewish genetics.” Acknowledging the distinctiveness of Jews is “fraught with peril,” but we must grapple with the hard evidence of “human differences” if we seek to understand the new age of genetics.

Although he readily acknowledges the formative role of culture and environment, Ostrer believes that Jewish identity has multiple threads, including DNA. He offers a cogent, scientifically based review of the evidence, which serves as a model of scientific restraint.

“On the one hand, the study of Jewish genetics might be viewed as an elitist effort, promoting a certain genetic view of Jewish superiority,” he writes. “On the other, it might provide fodder for anti-Semitism by providing evidence of a genetic basis for undesirable traits that are present among some Jews. These issues will newly challenge the liberal view that humans are created equal but with genetic liabilities.”

Jews, he notes, are one of the most distinctive population groups in the world because of our history of endogamy. Jews — Ashkenazim in particular — are relatively homogeneous despite the fact that they are spread throughout Europe and have since immigrated to the Americas and back to Israel. The Inquisition shattered Sephardi Jewry, leading to far more incidences of intermarriage and to a less distinctive DNA.

In traversing this minefield of the genetics of human differences, Ostrer bolsters his analysis with volumes of genetic data, which are both the book’s greatest strength and its weakness. Two complementary books on this subject — my own “Abraham’s Children: Race, Identity, and the DNA of the Chosen People” and “Jacob’s Legacy: A Genetic View of Jewish History” by Duke University geneticist David Goldstein, who is well quoted in both “Abraham’s Children” and “Legacy” — are more narrative driven, weaving history and genetics, and are consequently much more congenial reads.

A ‘people’

The concept of the “Jewish people” remains controversial. The Law of Return, which establishes the right of Jews to come to Israel, is a central tenet of Zionism and a founding legal principle of the State of Israel. The DNA that tightly links Ashkenazi, Sephardi and Mizrahi, three prominent culturally and geographically distinct Jewish groups, could be used to support Zionist territorial claims — except, as Ostrer points out, some of the same markers can be found in Palestinians, our distant genetic cousins, as well. Palestinians, understandably, want their own right of return.

That disagreement over the meaning of DNA also pits Jewish traditionalists against a particular strain of secular Jewish liberals that has joined with Arabs and many non-Jews to argue for an end to Israel as a Jewish nation. Their hero is Shlomo Sand, an Austrian-born Israeli historian who reignited this complex controversy with the 2008 publication of “The Invention of the Jewish People.”

Sand contends that Zionists who claim an ancestral link to ancient Palestine are manipulating history. But he has taken his thesis from novelist Arthur Koestler’s 1976 book, “The Thirteenth Tribe,” which was part of an attempt by post-World War II Jewish liberals to reconfigure Jews not as a biological group, but as a religious ideology and ethnic identity.

The majority of the Ashkenazi Jewish population, as Koestler, and now Sand, writes, are not the children of Abraham but descendants of pagan Eastern Europeans and Eurasians, concentrated mostly in the ancient Kingdom of Khazaria in what is now Ukraine and Western Russia. The Khazarian nobility converted during the early Middle Ages, when European Jewry was forming.

Although scholars challenged Koestler’s and now Sand’s selective manipulation of the facts — the conversion was almost certainly limited to the tiny ruling class and not to the vast pagan population — the historical record has been just fragmentary enough to titillate determined critics of Israel, who turned both Koestler’s and Sand’s books into roaring best-sellers.

Fortunately, re-creating history now depends not only on pottery shards, flaking manuscripts and faded coins, but on something far less ambiguous: DNA. Ostrer’s book is an impressive counterpoint to the dubious historical methodology of Sand and his admirers. And, as a co-founder of the Jewish HapMap — the study of haplotypes, or blocks of genetic markers, that are common to Jews around the world — he is well positioned to write the definitive response.

In accord with most geneticists, Ostrer firmly rejects the fashionable postmodernist dismissal of the concept of race as genetically naive, opting for a more nuanced perspective.

Mapping the human gene

When the human genome was first mapped a decade ago, Francis Collins, then head of the National Genome Human Research Institute, said: “Americans, regardless of ethnic group, are 99.9% genetically identical.” Added J. Craig Venter, who at the time was chief scientist at the private firm that helped sequenced the genome, Celera Genomics, “Race has no genetic or scientific basis.” Those declarations appeared to suggest that “race,” or the notion of distinct but overlapping genetic groups, is “meaningless.”

But Collins and Venter have issued clarifications of their much-misrepresented comments. Almost every minority group has faced, at one time or another, being branded as racially inferior based on a superficial understanding of how genes peculiar to its population work. The inclination by politicians, educators and even some scientists to underplay our separateness is certainly understandable. But it’s also misleading. DNA ensures that we differ not only as individuals, but also as groups.

However slight the differences (and geneticists now believe that they are significantly greater than 0.1%), they are defining. That 0.1% contains some 3 million nucleotide pairs in the human genome, and these determine such things as skin or hair color and susceptibility to certain diseases. They contain the map of our family trees back to the first modern humans.

Both the human genome project and disease research rest on the premise of finding distinguishable differences between individuals and often among populations. Scientists have ditched the term “race,” with all its normative baggage, and adopted more neutral terms, such as “population” and “clime,” which have much of the same meaning. Boiled down to its essence, race equates to “region of ancestral origin.”

‘Jewish diseases’

Ostrer has devoted his career to investigating these extended family trees, which help explain the genetic basis of common and rare disorders. Today, Jews remain identifiable in large measure by the 40 or so diseases we disproportionately carry, the inescapable consequence of inbreeding. He traces the fascinating history of numerous “Jewish diseases,” such as Tay-Sachs, Gaucher, Niemann-Pick, Mucolipidosis IV, as well as breast and ovarian cancer. Indeed, 10 years ago I was diagnosed as carrying one of the three genetic mutations for breast and ovarian cancer that mark my family and me as indelibly Jewish, prompting me to write “Abraham’s Children.”

Like East Asians, the Amish, Icelanders, Aboriginals, the Basque people, African tribes and other groups, Jews have remained isolated for centuries because of geography, religion or cultural practices. It’s stamped on our DNA. As Ostrer explains in fascinating detail, threads of Jewish ancestry link the sizable Jewish communities of North America and Europe to Yemenite and other Middle Eastern Jews who have relocated to Israel, as well as to the black Lemba of southern Africa and to India’s Cochin Jews. But, in a twist, the links include neither the Bene Israel of India nor Ethiopian Jews. Genetic tests show that both groups are converts, contradicting their founding myths.

Why, then, are Jews so different looking, usually sharing the characteristics of the surrounding populations? Think of red-haired Jews, Jews with blue eyes or the black Jews of Africa. Like any cluster — a genetic term Ostrer uses in place of the more inflammatory “race” — Jews throughout history moved around and fooled around, although mixing occurred comparatively infrequently until recent decades. Although there are identifiable gene variations that are common among Jews, we are not a “pure” race. The time machine of our genes may show that most Jews have a shared ancestry that traces back to ancient Palestine but, like all of humanity, Jews are mutts.

About 80% of Jewish males and 50% of Jewish females trace their ancestry back to the Middle East. The rest entered the “Jewish gene pool” through conversion or intermarriage. Those who did intermarry often left the faith in a generation or two, in effect pruning the Jewish genetic tree. But many converts became interwoven into the Jewish genealogical line. Reflect on the iconic convert, the biblical Ruth, who married Boaz and became the great-grandmother of King David. She began as an outsider, but you don’t get much more Jewish than the bloodline of King David!

Jewish intelligence

To his credit, Ostrer also addresses the third rail of discussions about Jewishness and race: the issue of intelligence. Jews were latecomers to the age of freethinking. While the Enlightenment swept through Christian Europe in the 17th century, the Haskalah did not gather strength until the early 19th century. By the beginning of the new millennium, however, Jews were thought of as among the smartest people on earth. The trend is most prominent in America, which has the largest concentration of Jews outside Israel and a history of tolerance.

Although Jews make up less than 3% of the population, they have won more than 25% of the Nobel Prizes awarded to American scientists since 1950. Jews also account for 20% of this country’s chief executives and make up 22% of Ivy League students. Psychologists and educational researchers have pegged their average IQ at 107.5 to 115, with their verbal IQ at more than 120, a stunning standard deviation above the average of 100 found in those of European ancestry. Like it or not, the IQ debate will become an increasingly important issue going forward, as medical geneticists focus on unlocking the mysteries of the brain.

Many liberal Jews maintain, at least in public, that the plethora of Jewish lawyers, doctors and comedians is the product of our cultural heritage, but the science tells a more complex story. Jewish success is a product of Jewish genes as much as of Jewish moms.

Is it “good for the Jews” to be exploring such controversial subjects? We can’t avoid engaging the most challenging questions in the age of genetics. Because of our history of endogamy, Jews are a goldmine for geneticists studying human differences in the quest to cure disease. Because of our cultural commitment to education, Jews are among the top genetic researchers in the world.

As humankind becomes more genetically sophisticated, identity becomes both more fluid and more fixed. Jews in particular can find threads of our ancestry literally anywhere, muddying traditional categories of nationhood, ethnicity, religious belief and “race.” But such discussions, ultimately, are subsumed by the reality of the common shared ancestry of humankind. Ostrer’s “Legacy” points out that — regardless of the pros and cons of being Jewish — we are all, genetically, in it together. And, in doing so, he gets it just right.

Jon Entine is the founder and director of the Genetic Literacy Project at George Mason University, where he is senior research fellow at the Center for Health and Risk Communication.

http://www.haaretz.com/jewish-world/...xpert-1.428664
 
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